Fig. 6.

Effects of CDRE consumption on changes in regulators of the insulin signaling pathway associated to a HFM in PMBC from healthy participants. Phosphorylation levels of IKK (A), and JNK1/2 (B), and protein levels of PTP1B (C) were measured by Western blot in PMBC isolated at time 0 and 3 h after the consumption of a HFM and placebo or CDRE. Representative images are shown in the left panel. Bands were quantified and values referred to total protein (IKK, JNK1/2) or β-actin levels (PTP1B). Results are shown as means ± SE. ^#Significantly different comparing 0 vs. 3 h; and *significant different from placebo (p < 0.05, one-way ANOVA).