TABLE 1.
Percentage of Ki‐67 positive tumour cells in both, xenograft or multinodular tumour model
| Group | % of positive staining Ki‐67 cells | |
|---|---|---|
| Xenograft model | Control 1) w/o laser and w/o PEG‐HGNs‐sEVshpMSCs | 90.9 ± 14.4 |
| Control 2) w laser and w/o PEG‐HGNs‐sEVshpMSCs | 93.6 ± 9.3 | |
| Control 3) w/o laser and w PEG‐HGNs‐sEVshpMSCs | 96.3 ± 5.9 | |
| w PEG‐HGNs‐sEVshpMSCs and w laser | 1.4 ± 2.2 | |
| Multinodular model | Control 1) w/o laser and w/o PEG‐HGNs‐sEVshpMSCs | 86.2 ± 17.5 |
| Control 2) w laser and w/o PEG‐HGNs‐sEVshpMSCs | 65.3 ± 28 | |
| Control 3) w/o laser and w PEG‐HGNs‐sEVshpMSCs | 66.9 ± 22.8 | |
| w PEG‐HGNs‐sEVshpMSCs and w laser | 5.9 ± 5.4 |
Protein expression was studied in all groups by counting positive and negative cells in three acquisition images from all animals using ImageJ software. Data was expressed as the percentage of positive cells.