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. 2022 Feb 21;9(2):e31116. doi: 10.2196/31116

Table 5.

Outcomes from included studies (N=17).

Study Outcome Study quality rating Hedges g P value Intervention effect
Cain et al [61] Insomnia 3 0.576 .06 The study was marginally significant in reducing insomnia symptoms following the intervention for women in the CBT-Ia group.
Felder et al [57] Insomnia 3 0.688 <.001 Results from the study found those who received digital CBT-I experienced significantly greater reductions in insomnia symptom severity compared with women in the control group.
Kalmbach et al [60] Insomnia 1 0.403 .06 CBT-I patients reported lower insomnia symptoms on the ISIb and PSQIc after treatment than controls; however, this was marginally significant.
Heller et al [52] Anxiety and depression 1 Anxiety: 0.076; depression: –0.10 Anxiety: .70; depression: .96 No significant differences were found between the intervention group and the control group for both anxiety and depression.
Chan et al [62] Anxiety and depression 1 Anxiety: –0.045; depression: 0.219 Anxiety: .56; depression: .02 Scores of depression significantly decreased in the intervention group when compared with the control group; however, scores of anxiety did not significantly decrease when comparing the intervention group with the control group.
Duffecy et al [56] Depression 3 0.696 .29 Study results participants in the web-based intervention had reduced scores of depression when compared with the control group; however, this was not significant.
Haga et al [55] Depression 1 0.121 .03 At all 4 follow-up time points of this study, pregnant people participating in the Mamma Mia had significantly lower depressive scores in comparison with the control group.
Yang et al [63] Anxiety and depression 2 Anxiety: 0.868; depression: 0.933 Anxiety: <.001; depression: <.001 In comparison with the control group who had received in-person treatment, the participants belonging to the WeChat intervention reported significant reduction in anxiety and depressive scores.
Krusche et al [53] Anxiety and depression 1 Anxiety: 0.641; depression: 0.677 Anxiety: .02; depression: .01 There was a significant reduction in scores between intervention and waitlist groups, regarding anxiety and depressive symptoms.
Loughnan et al [54] Anxiety and depression 0 Anxiety: 0.588; depression: 0.300 Anxiety: .01; depression: .19 The analysis indicates that the iCBTd group demonstrated no significant group by time interactions for depression symptom reduction. However, the iCBT group showed significantly reduced anxiety symptoms.
Dennis-Tiwary et al [58] Anxiety and depression 1 Anxiety: –0.305; depression: 0.068 Anxiety: .40; depression: .85 Results found that individuals in the ABMTe group did not show significant improvements in anxiety and depression.
Sun et al [64] Anxiety and depression 2 Anxiety: 0.182; depression: 0.155 Anxiety: .24; depression: .08 Mindfulness training participants reported a decreased risk of positive depressive symptoms and anxiety symptoms in comparison with controls; however, this was not significant.
Forsell et al [65] Depression 1 0.739 .02 Depression symptoms significantly decreased in the intervention group compared with the control group.
Scherer et al [51] Anxiety 0 0.096 .71 Levels of stress and anxiety did not significantly decrease in the intervention group when compared with the control group.
Barrera et al [59] Depression 3 –0.425 .16 Following the intervention, depression scores in the intervention group did not statistically differ from the control group.
Hanprasertpong et al [66] Anxiety 3 0.010 .93 Anxiety following the intervention was reduced significantly in both groups in comparison with baseline; however, no significant differences existed among groups after the intervention.
Jareethum et al [67] Anxiety 3 0.624 .02 In comparison with the control group who received treatment as usual, women receiving SMS text messages during the antenatal period demonstrated significantly decreased levels of anxiety.

aCBT-I: cognitive behavioral therapy for insomnia.

bISI: Insomnia Severity Index.

cPSQI: Pittsburgh Sleep Quality Index.

diCBT: internet-based CBT.

eABMT: attention bias modification training.