Table 7.
Circadian rhythm parameters of NPY, AGRP, POMC and CART in hypothalamus, as determined by cosinor analyses
Index | Group | NPY | AGRP | POMC | CART |
---|---|---|---|---|---|
Mesor | CON | 1.06 ± 0.03 | 1.12 ± 0.06 | 1.11 ± 0.06 | 1.01 ± 0.03 |
CORT | 0.66 ± 0.02** | 0.69 ± 0.03** | 0.69 ± 0.07** | 0.67 ± 0.01** | |
Amplitude | CON | 0.36 ± 0.05 | 0.42 ± 0.10 | 0.46 ± 0.08 | 0.40 ± 0.04 |
CORT | 0.10 ± 0.03** | 0.10 ± 0.05** | 0.16 ± 0.10** | 0.10 ± 0.01** | |
Acrophase, h | CON | 8.25 ± 0.44 | 8.86 ± 0.77 | 18.72 ± 0.63 | 20.03 ± 0.35 |
CORT | ND | ND | ND | ND |
Values are means ± SEM. *P < 0.05, **P < 0.01, compared with CON group. ND represents not determined as there was no circadian rhythm