Table 3. Analysis of Acylcarnitines, Lipids, and Hexose across Four Visits (n = 141)^a.

metabolites	P valueb	FDR-adjustedc	ICC	95% CI
Acylcarnitines
C0	0.1049	0.2248	0.76	0.70–0.81
C2	0.0010	0.0331	0.51	0.43–0.59
C3	0.0127	0.0922	0.73	0.67–0.79
C4	0.8707	0.9034	0.79	0.74–0.83
C6 (C4:1-DC)	0.4683	0.5669	0.74	0.68–0.80
C8	0.6985	0.7711	0.71	0.65–0.77
C10	0.4372	0.5500	0.67	0.60–0.73
C10:1	0.6394	0.7116	0.60	0.52–0.67
C14:1	0.2559	0.3797	0.65	0.58–0.72
C18:1	0.4570	0.5631	0.66	0.59–0.73
lysoPhosphatidylcholines
lysoPC a C16:0	0.1959	0.3257	0.68	0.61–0.74
lysoPC a C16:1	0.2191	0.3422	0.61	0.54–0.69
lysoPC a C17:0	0.1457	0.2692	0.74	0.69–0.80
lysoPC a C18:0	0.0867	0.2160	0.64	0.56–0.71
lysoPC a C18:1	0.0060	0.0753	0.65	0.58–0.72
lysoPC a C18:2	0.0006	0.0331	0.69	0.63–0.75
lysoPC a C20:3	0.0892	0.2160	0.65	0.58–0.72
lysoPC a C20:4	0.0206	0.1015	0.66	0.58–0.72
lysoPC a C28:0	0.6199	0.7116	0.32	0.23–0.41
lysoPC a C28:1	0.9975	0.9975	0.85	0.82–0.89
Phosphatidylcholines
PC aa C24:0	0.6312	0.7116	0.31	0.23–0.41
PC aa C28:1	0.0526	0.1728	0.84	0.80–0.87
PC aa C30:0	0.4388	0.5500	0.50	0.41–0.58
PC aa C32:0	0.0728	0.2001	0.20	0.12–0.29
PC aa C32:1	0.2277	0.3453	0.46	0.37–0.54
PC aa C32:2	0.8331	0.8912	0.37	0.28–0.46
PC aa C32:3	0.0599	0.1857	0.57	0.50–0.65
PC aa C34:1	0.4424	0.5500	0.22	0.14–0.31
PC aa C34:2	0.4638	0.5664	0.15	0.07–0.24
PC aa C34:3	0.5461	0.6333	0.40	0.31–0.49
PC aa C34:4	0.9465	0.9675	0.58	0.50–0.66
PC aa C36:0	0.0544	0.1746	0.78	0.73–0.83
PC aa C36:1	0.2806	0.4119	0.59	0.51–0.66
PC aa C36:2	0.0876	0.2160	0.21	0.13–0.30
PC aa C36:3	0.4058	0.5318	0.22	0.14–0.31
PC aa C36:4	0.1075	0.2248	0.77	0.71–0.82
PC aa C36:5	0.0330	0.1231	0.69	0.62–0.75
PC aa C36:6	0.2143	0.3422	0.69	0.62–0.75
PC aa C38:0	0.0312	0.1208	0.81	0.77–0.85
PC aa C38:1	0.0984	0.2248	0.42	0.33–0.51
PC aa C38:3	0.3805	0.5098	0.22	0.14–0.31
PC aa C38:4	0.0270	0.1164	0.31	0.22–0.40
PC aa C38:5	0.0198	0.1012	0.71	0.64–0.77
PC aa C38:6	0.0002	0.0259	0.78	0.73–0.83
PC aa C40:2	0.1855	0.3160	0.45	0.36–0.54
PC aa C40:3	0.0054	0.0745	0.26	0.17–0.35
PC aa C40:4	0.6319	0.7116	0.68	0.61–0.74
PC aa C40:5	0.3595	0.4931	0.68	0.61–0.75
PC aa C40:6	0.0072	0.0764	0.77	0.72–0.82
PC aa C42:0	0.0141	0.0966	0.61	0.54–0.68
PC aa C42:1	0.4295	0.5500	0.48	0.39–0.56
PC aa C42:2	0.9711	0.9782	0.55	0.47–0.63
PC aa C42:4	0.1056	0.2248	0.38	0.29–0.47
PC aa C42:5	0.5384	0.6309	0.26	0.17–0.35
PC aa C42:6	0.1225	0.2415	0.59	0.51–0.66
PC ae C30:0	0.4085	0.5318	0.65	0.57–0.71
PC ae C30:1	0.8101	0.8803	0.23	0.15–0.32
PC ae C30:2	0.4786	0.5743	0.72	0.66–0.78
PC ae C32:1	0.0012	0.0331	0.74	0.68–0.79
PC ae C32:2	0.0096	0.0779	0.78	0.73–0.83
PC ae C34:0	0.2207	0.3422	0.75	0.70–0.81
PC ae C34:1	0.1397	0.2678	0.69	0.62–0.75
PC ae C34:2	0.0704	0.2001	0.68	0.61–0.74
PC ae C34:3	0.2159	0.3422	0.29	0.20–0.38
PC ae C36:0	0.1764	0.3045	0.68	0.61–0.74
PC ae C36:1	0.0924	0.2178	0.75	0.69–0.80
PC ae C36:2	0.2018	0.3315	0.74	0.68–0.79
PC ae C36:3	0.0734	0.2001	0.66	0.59–0.73
PC ae C36:4	0.1673	0.2960	0.70	0.63–0.76
PC ae C36:5	0.0309	0.1208	0.76	0.70–0.81
PC ae C38:0	0.0051	0.0745	0.71	0.65–0.77
PC ae C38:1	0.0008	0.0331	0.18	0.10–0.27
PC ae C38:2	0.1072	0.2248	0.62	0.55–0.69
PC ae C38:3	0.1194	0.2388	0.70	0.64–0.76
PC ae C38:4	0.0315	0.1208	0.73	0.67–0.79
PC ae C38:5	0.0087	0.0779	0.69	0.62–0.75
PC ae C38:6	0.0039	0.0745	0.79	0.74–0.84
PC ae C40:1	0.0612	0.1857	0.66	0.59–0.73
PC ae C40:2	0.0051	0.0745	0.69	0.62–0.75
PC ae C40:3	0.0521	0.1728	0.70	0.64–0.76
PC ae C40:4	0.0107	0.0820	0.50	0.42–0.59
PC ae C40:5	0.0093	0.0779	0.69	0.62–0.75
PC ae C40:6	0.0041	0.0745	0.79	0.74–0.84
PC ae C42:1	0.9623	0.9765	0.51	0.43–0.59
PC ae C42:2	0.5176	0.6158	0.45	0.36–0.54
PC ae C42:3	0.1280	0.2488	0.39	0.30–0.48
PC ae C42:4	0.1765	0.3045	0.63	0.56–0.70
PC ae C42:5	0.0853	0.2160	0.71	0.65–0.77
PC ae C44:3	0.0197	0.1012	0.34	0.26–0.44
PC ae C44:4	0.5395	0.6309	0.54	0.46–0.62
PC ae C44:5	0.1130	0.2327	0.44	0.36–0.53
PC ae C44:6	0.3409	0.4800	0.44	0.36–0.53
Sphingomyelins
SM (OH) C14:1	0.0258	0.1164	0.89	0.85–0.91
SM (OH) C16:1	0.0184	0.1012	0.45	0.36–0.54
SM (OH) C22:1	0.0264	0.1164	0.73	0.67–0.79
SM (OH) C22:2	0.0072	0.0764	0.79	0.74–0.84
SM (OH) C24:1	0.1882	0.3167	0.45	0.36–0.54
SM C16:0	0.0094	0.0779	0.66	0.59–0.72
SM C16:1	0.0751	0.2001	0.75	0.70–0.80
SM C18:0	0.1606	0.2878	0.22	0.14–0.31
SM C18:1	0.0619	0.1857	0.30	0.21–0.39
SM C20:2	0.0288	0.1204	0.54	0.46–0.62
SM C24:0	0.1148	0.2330	0.64	0.57–0.71
SM C24:1	0.0154	0.0966	0.61	0.53–0.68
SM C26:0	0.8653	0.9034	0.44	0.36–0.53
SM C26:1	0.0449	0.1589	0.67	0.61–0.74
hexose (H1)	0.2868	0.4150	0.37	0.28–0.46

^aAbbreviations are as follows. Cx:y: x = number of carbons in the fatty acid side chain, y = number of double bonds in the fatty acid side chain; DC: decarboxyl; OH: hydroxyl; lysoPC: lysophosphatidylcholine; PC: phosphatidylcholine; aa: acyl–acyl; ae: acyl–alkyl; SM: sphingomyelin; CI: confidence interval; ICC: intraclass correlation coefficient.

^bP values are from repeated-measures ANOVA.

^cFDR-adjusted P values are adjusted for multiple comparisons by the Benjamini–Hochberg procedure.