Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 22;13:835830. doi: 10.3389/fimmu.2022.835830

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Taus, Hofmann, Ibarrondo, Hausner, Fulcher, Krogstad, Ferbas, Tobin, Rimoin, Aldrovandi and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Vaccination of persons without prior SARS-CoV-2 infection elicits CD8⁺ T cell targeting of spike similar to natural infection. Across the 44 persons with recent SARS-CoV-2 infection ( Figure 3 ) and 22 persons after vaccination without prior SARS-CoV-2 infection ( Figure 5 ), CD8⁺ T cell responses against spike defined by ELISpot were compared. Pearson correlation p values are indicated. (A) The mean percentage contribution of each pool to the total spike response (log₁₀ transformed) is plotted between the two groups. (B) The percentage of persons responding against each pool is plotted between the two groups.