TABLE 2.

CORRELATIONS BETWEEN CITRULLINATED HISTONE H3: DNA COMPLEXES AND CLINICAL VARIABLES IN SERUM SAMPLES

FEATURE	VARIABLE (N); MEDIAN	VARIABLE (N); MEDIAN	P Value
Sex	F (71); 1.469	M (176); 1.536	0.56224
Age	<60 (120); 1.531	>60 (127); 1.487	0.81405
Severity	Mild (20); 0.876	Moderate (18); 1.366	0.02047
Severity	Mild (20); 0.876	Severe (41); 1.642	0.00087
Severity	Mild (20); 0.876	Critical (156); 1.721	0.00003
Oxygen needs	None (14); 1.383	Low flow (83); 1.545	0.45673
Oxygen needs	None (14); 1.383	High flow (22); 2.154	0.01889
Oxygen needs	None (14); 1.383	Intubation (31); 2.227	0.06737
Oxygen needs	None (14); 1.383	Tracheostomy (27); 2.016	0.22420
Pneumonia	Absent (30); 0.679	Present (203); 1.642	1.62E-06
Renal insufficiency	Absent (227); 1.487	Present (6); 1.764	0.48807
Death	Alive (200); 1.474	Deceased (43); 1.609	0.96948
Need for ICU	ICU (73); 2.016	non-ICU (174); 1.402	0.00040
Comorbidities	Absent(183); 1.504	Present (45); 1.722	0.32151
CVD	Absent (178); 1.626	Present (50); 1.305	0.27970
Hypertension	Absent (137); 1.643	Present (91); 1.480	0.03985
Diabetes mellitus	Absent(185); 1.556	Present (43); 1.504	0.48271
CHF	Absent (209); 1.584	Present (19); 1.168	0.16524
CKD	Absent (186); 1.716	Present (42); 0.995	0.00006
Obesity	Absent (207); 1.527	Present (21); 1.926	0.11416
Hematologic malignancy	Absent (177); 1.654	Present (51); 1.285	0.07943
Solid malignancy	Absent (204); 1.630	Present (21); 1.197	0.03401
Neurologic/Psychiatric disease	Absent (182); 1.560	Present (46); 1.492	0.29857
Autoimmunity	Absent (180); 1.643	Present (48); 1.194	0.05443
Chronic Respiratory disease	Absent (206); 1.531	Present (22); 1.629	0.85031
Liver disease	Absent (210); 1.551	Present (18); 1.425	0.61260
Solid organ transplant	Absent (211); 1.584	Present (17); 0.882	0.01140

ICU: intensive care unit; CVD: cardiovascular disease; CHF: congestive heart failure; CKD: chronic kidney disease