TABLE 1.
MICs and MBCs (in micrograms/milliliter) of LY333328, teicoplanin, and vancomycin for E. faecalis strains with various resistance phenotypes
| Antibiotic |
E. faecalis JH2-2 (susceptible)
|
E. faecalis BM4281 (VanB)
|
E. faecalis BM4316 (VanA)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| MIC in:
|
MBC | MIC in:
|
MBC | MIC in:
|
MBC | ||||
| Agar | Broth | Agar | Broth | Agar | Broth | ||||
| LY333328 | 2 | 0.25 | 1 | 2 | 0.25 | 1 | 2 | 0.25 | 16 |
| Teicoplanin | 1 | 1 | 16 | 1 | 1 | 32 | 64 | 8 | >128 |
| Vancomycin | 2 | 2 | 128 | 256 | 128 | >128 | 256 | >128 | >128 |