TABLE 3.

Results of treatment with LY333328, vancomycin, and teicoplanin for 5 days in rabbits with experimental aortic endocarditis due to E. faecalis with various resistance phenotypes

Regimen	Mean log10 CFU/g of vegetation ± SD (no. of animals) for the indicated E. faecalis strain (phenotype)
	JH2-2 (susceptible)	BM4281 (VanB)	BM4316 (VanA)
Control	9.9 ± 1.1 (8)	8.5 ± 1.0 (10)	8.9 ± 0.6 (8)
Vancomycin	7.3 ± 1.1a (6)	8.4 ± 1.1 (11)	Not done
Teicoplanin	6.5 ± 0.7ab (9)	6.2 ± 1.6a (13)	7.9 ± 1.5 (5)
LY333328	8.1 ± 0.9a (6)	5.7 ± 1.5bc (8)	6.8 ± 1.8a (7)

^aP < 0.05 versus control animals. 

^bP < 0.05 versus LY333328. 

^cP < 0.01 versus vancomycin.