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. Author manuscript; available in PMC: 2022 May 24.
Published in final edited form as: Sci Transl Med. 2021 Nov 24;13(621):eabg2612. doi: 10.1126/scitranslmed.abg2612

Fig. 4. Dysregulation of specific stress response genes influences the DD phenotype.

Fig. 4.

(A) Viable cell counts are shown for WT H37Rv, ∆mshA, and ∆mshA::mshA after starvation and 5 days of RIF or DMSO exposure. Data are representative of 2 experiments with 3 biological replicates each. Data were analyzed using a mixed-effects analysis with Sidak’s multiple comparisons test. (B) Viable cell counts are shown for parent wild type (WT) Erdman Mtb strain, ∆icl1–2, and ∆icl1–2::icl1 after starvation and 5 days of RIF or DMSO exposure. Data are representative of 3 experiments with 3 biological replicates each. Data were analyzed with a two-way ANOVA with Sidak’s multiple comparisons test. *adj p < 0.05, **adj p < 0.01, ***adj p < 0.001, ****adj p < 0.0001.