Figure 6. Impact of nicotine delivery rates on CPT performance.
This figure illustrates the throughput scores (higher scores indicate better performance) on a Continuous Performance Task (CPT) under different nicotine delivery rates. Participants received saline and nicotine (total dose, 1.0 mg per 70 kg body weight), infused over 1 minute (1 mg nicotine/minute), 2.5 minutes (0.4 mg nicotine/minute), 5 minutes (0.2 mg nicotine/minute) and 10 min (0.1 mg nicotine/minute). Error bars reflect standard error of the mean. * p < 0.05 for pairwise comparisons of the nicotine condition with the saline condition. For details, please see section 3.4 of the manuscript.