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| DMT | ARR* | CDP-6 months* | Discontinuation§ | Reference | |||
| RR | 95%CI | HR | 95%CI | HR | 95%CI | 12 | |
| Interferon beta | 0.65 | 0.48–0.88 | 0.93 | 0.71–1.20 | - | ||
| Siponimod | 0.59 | 0.35–0.99 | 0.50 | 0.35–0.74 | 0.87 | 0.64–1.18 | |
ARR = annual relapse rate; CDP = confirmed disability progression; HR = Hazard ratio; RR = relative risk; SE Standard error.
* Drug compared with placebo; § Siponimod versus interferon beta 1b.
