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. 2022 Mar 8;17(3):e0264123. doi: 10.1371/journal.pone.0264123

Table 3. Disease-modifying therapies (DMTs) costs.

DMT Dose Unit per pack List price (€) Price ex-factory Administration and monitoring costs Reference
INF bera-1b (Extavia®) 0,25 mg every 48 hours 5 vials € 470.9 € 285.3 € 1,137 first year € 412 after first year 20
INF bera-1b (Betaferon®) 0,25 mg every 48 hours 15 vials € 1412.8 € 856.01
Siponimod 2 mg/day 28 tablets € 3,120.7 € 1,890.9 € 1,272 first year € 309 after first year 20