Table 3.
Demographic and clinical parameters according to the survival status of all patients at 3 months
| TotalN: 944 | SurvivorsN: 936 | NonsurvivorsN: 8 | P | ||
|---|---|---|---|---|---|
| Study groups, n/N (%) | Control group | 421/944 (44.6) | 420/936 (44.9) | 1/8 (12.5) | 0.082 |
| COVID-19 group | 523/944 (55.4) | 516/936 (55.1) | 7/8 (87.5) | ||
| Age, years, median (IQR) | 46.0 (37.0–55.0) | 46.0 (36.0–55.0) | 59.0 (54.0–65.0) | 0.001 | |
| Gender, n/N (%) | Male | 532/944 (56.4) | 527/936 (56.3) | 5/8 (62.5) | 1.000 |
| Smoking, n/N (%) | Never smoked | 621/885 (70.2) | 616/877 (70.2) | 5/8 (62.5) | 0.758 |
| Current smoker | 25/885 (2.8) | 25/877 (2.9) | 0/8 (0.0) | ||
| Former smoker | 239/885 (2.7) | 236/877 (26.9) | 3/8 (37.5) | ||
| Tx duration, years, median (IQR) | 6.0 (3.0–11.0) | 6.0 (3.0–11.0) | 8.0 (5.0–10.0) | 0.536 | |
| Donor type, n/N (%) | Living non-related | 90/944(9.5) | 88/936 (9.4) | 2/8 (25.0) | 0.071 |
| Living related | 638/944 (67.6) | 635/936 (67.8) | 3/8 (37.5) | ||
| Deceased | 216/944 (22.9) | 213/936 (22.8) | 3/8 (37.5) | ||
| Pneumonia finding on CT, n/N (%) | 317/435 (72.9) | 310/428 (72.4) | 7/7 (100.0) | 0.197 | |
| Clinical presentation, n/N (%) | Mild disease | 345/523 (66.0) | 344/516 (66.6) | 1/7 (14.4) | <0.001 |
| Moderate disease | 157/523 (30.0) | 155/516 (30.0) | 2/7 (28.6) | ||
| Severe-critical disease | 21/523(4.0) | 17/516 (3.3) | 4/7 (57.1) | ||
| Type of treatment, n/N (%) | Inpatient | 290/523 (55.4) | 283/516 (54.8) | 7/7 (100.0) | 0.019 |
| ICU admission, n/N (%) | 31/290 (10.7) | 25/283 (8.8) | 6/7 (85.7) | <0.001 | |
| Outcomes at 3 month follow-up, n/N (%) | Ongoing respiratory symptoms | 47/944 (5.0) | 42/936 (4.5) | 5/8 (62.5) | <0.001 |
| Re-hospitalization | 5/944 (0.5) | 2/936 (0.2) | 3/8 (37.5) | <0.001 | |
| Need for home oxygen therapy | 71/944 (7.5) | 66/936 (7.1) | 5/8 (62.5) | <0.001 | |
| Lower respiratory tract infection | 12/944 (1.3) | 7/936 (0.7) | 5/8 (62.5) | <0.001 | |
| Urinary tract infection | 47/944 (5.0) | 46/936 (4.9) | 1/8 (12.5) | 1.000 | |
| Acute rejection (biopsy proven) | 10/944 (1.1) | 9/936 (1.0) | 1/8 (12.5) | 0.082 | |
| Venous or arterial thromboembolic event | 5/944 (0.5) | 5/936 (0.5) | 0/8 (0.0) | 1.000 | |
| CMV infection/disease | 8/944 (0.8) | 7/936 (0.7) | 1/8 (12.5) | 0.066 | |
| BK virus infection | 13/944 (1.4) | 13/936 (1.4) | 0/8 (0.0) | 1.000 | |
P-values presented from the Chi-squared test Fisher's exact test, or Mann–Whitney U test.
IQR, interquartile range; CMV, cytomegalovirus; ICU, intensive care unit; CT, computed tomography; Tx, transplantation.