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. 2022 Feb 21;23(1):30. doi: 10.1186/s10194-022-01399-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The expression of CB1, CGRP and RAMP1 in the TG. IHC localization of CB1, CGRP and the functional CGRP receptor (by staining for RAMP1) in the TG. Blue represents cell nuclei; orange represents colocalization of CGRP (upper panel) or RAMP1 (lower panel) with CB1; globular regions represent neuronal somas and fibrous regions represent individual neuronal fibres. Large image scale corresponds to 50 mm, and the insert scale corresponds to 10 μm. The arrows mark unmyelinated C-fibres (upper panel) and myelinated Aδ-fibres (lower panel)