Table 2.
Significant and suggestive association results for LPAx
| rsID | Chra | Positiona | REF | ALT | P value | MAF | Locus | Effect size (s.e.) |
|---|---|---|---|---|---|---|---|---|
| rs79453226 | chr4 | 4483114 | G | C | 1.91e-08 | 0.036 | STX18 (intron) | 0.421 (0.074) |
| rs11829294 | chr12 | 3014153 | C | T | 2.40e-08 | 0.145 | TEAD4 (intron) | − 0.231 (0.041) |
| rs10774094 | chr12 | 3014630 | C | A | 5.21e-08 | 0.160 | TEAD4 (intron) | − 0.214 (0.039) |
| rs12322215 | chr12 | 3001421 | G | T | 1.08e-07 | 0.142 | TEAD4 (intron) | − 0.215 (0.040) |
| rs10128796 | chr12 | 3003552 | G | A | 1.11e-07 | 0.142 | TEAD4 (intron) | − 0.214 (0.040) |
| rs73916918 | chr19 | 376264 | C | T | 1.17e-07 | 0.020 | THEG (5’ UTR) | 0.522 (0.097) |
| rs59359613 | chr1 | 113154555 | C | T | 1.83e-07 | 0.023 | intergenic | 0.465 (0.088) |
| rs16913588 | chr9 | 28733517 | T | C | 2.05e-07 | 0.036 | intergenic | 0.396 (0.075) |
| rs58545250 | chr1 | 113172866 | T | C | 2.14e-07 | 0.024 | RP11-389O22.4 (downstream) | 0.438 (0.083) |
| rs61114884 | chr12 | 3004684 | T | A | 2.39e-07 | 0.135 | TEAD4 (intron) | − 0.210 (0.040) |
| rs28411755 | chr4 | 124309484 | T | C | 3.40e-07 | 0.025 | intergenic | 0.431 (0.083) |
| rs7657348 | chr4 | 124310584 | A | G | 3.40e-07 | 0.025 | intergenic | 0.431 (0.083) |
| rs76946462 | chr18 | 22326760 | A | G | 3.96e-07 | 0.057 | intergenic | 0.278 (0.054) |
| rs77039990 | chr18 | 22327483 | G | A | 3.97e-07 | 0.057 | intergenic | 0.278 (0.054) |
| rs76500624 | chr18 | 22326662 | G | A | 3.97e-07 | 0.057 | intergenic | 0.278 (0.054) |
| rs75050632 | chr18 | 22327123 | G | A | 4.03e-07 | 0.057 | intergenic | 0.277 (0.054) |
| rs115606157 | chr3 | 108839197 | T | G | 4.53e-07 | 0.030 | TRAT1 (intron) | 0.385 (0.07) |
| rs73690518 | chr8 | 65242418 | C | T | 4.80e-07 | 0.048 | intergenic | 0.355 (0.070) |
| rs17031018 | chr1 | 113100296 | A | G | 5.27e-07 | 0.035 | LRIG2 (intron) | 0.377 (0.074) |
| rs61917974 | chr12 | 3011978 | T | C | 6.33e-07 | 0.109 | TEAD4 (intron) | − 0.223 (0.044) |
| rs12296242 | chr12 | 3006641 | G | C | 6.49e-07 | 0.133 | TEAD4 (intron) | − 0.202 (0.040) |
| rs143601180 | chr3 | 4370781 | A | G | 6.56e-07 | 0.032 | SUMF1 (intron) | 0.383 (0.076) |
| rs79946490 | chr3 | 4385952 | C | T | 6.64e-07 | 0.032 | SUMF1 (intron) | 0.383 (0.076) |
| rs17031120 | chr1 | 113144809 | T | C | 7.12e-07 | 0.021 | intergenic | 0.462 (0.092) |
| rs2163633 | chr2 | 81884390 | C | A | 7.36e-07 | 0.046 | intergenic | − 0.350 (0.070) |
| rs6716465 | chr2 | 81871292 | G | C | 7.43e-07 | 0.045 | intergenic | − 0.350 (0.070) |
| rs11062457 | chr12 | 3010236 | C | T | 7.44e-07 | 0.145 | TEAD4 (intron) | − 0.201 (0.040) |
| rs72921448 | chr2 | 81824332 | T | C | 7.44e-07 | 0.045 | intergenic | − 0.350 (0.070) |
| rs2286647 | chr12 | 3010912 | C | T | 7.46e-07 | 0.145 | TEAD4 (intron) | − 0.201 (0.040) |
| rs116629423 | chr2 | 81858789 | A | G | 7.47e-07 | 0.045 | intergenic | − 0.350 (0.070) |
| rs143923810 | chr12 | 2988024 | C | T | 7.73e-07 | 0.139 | TEAD4 (intron) | − 0.194 (0.039) |
| rs10493588 | chr1 | 76227682 | C | T | 8.04e-07 | 0.057 | ST6GALNAC3 (intron) | 0.279 (0.056) |
| rs17098434 | chr1 | 76232427 | G | A | 8.85e-07 | 0.057 | ST6GALNAC3 (intron) | 0.277 (0.056) |
| rs8025099 | chr15 | 91488748 | C | A | 9.06e-07 | 0.486 | CRAT37 (intron) | − 0.129 (0.026) |
| rs12318430 | chr12 | 3006040 | C | A | 9.75e-07 | 0.132 | TEAD4 (intron) | − 0.201 (0.040) |
| rs9424366 | chr1 | 24475103 | G | C | 9.86e-07 | 0.036 | NIPAL3 (downstream) | 0.349 (0.070) |
Ordered by significance
aNCBI build 38