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. 2022 Feb 17;27:15. doi: 10.1186/s11658-022-00310-2

Fig. 2.

Fig. 2

DANCR downregulation ameliorated ox-LDL-induced endothelial injury in vitro. VSMCs and HUVECs were transfected with si-DANCR or si-NC and then treated with 50 μg/ml ox-LDL for 48 h. A DANCR expression was detected by qRT-PCR. B CCK-8 assay. C Flow cytometry assay. D Expression of apoptosis-related proteins was detected by Western blot. The original images are shown in Additional file 1. E Expression of inflammatory cytokines was detected by ELISA assay. F, G Levels of MDA (F) and SOD (G) were evaluated by specific detection kits. Each experiment was repeated three independent times. **p < 0.01 and ***p < 0.001