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. 2022 Feb 17;27:15. doi: 10.1186/s11658-022-00310-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — DANCR downregulation ameliorated ox-LDL-induced endothelial injury in vitro. VSMCs and HUVECs were transfected with si-DANCR or si-NC and then treated with 50 μg/ml ox-LDL for 48 h. A DANCR expression was detected by qRT-PCR. B CCK-8 assay. C Flow cytometry assay. D Expression of apoptosis-related proteins was detected by Western blot. The original images are shown in Additional file 1. E Expression of inflammatory cytokines was detected by ELISA assay. F, G Levels of MDA (F) and SOD (G) were evaluated by specific detection kits. Each experiment was repeated three independent times. **p < 0.01 and ***p < 0.001