Table 5.
Comparison of clinical features and symptoms severity in patients with different genotypes of rs12294045
| Items | Classification | CC(117) | TT(20) | CT(96) | χ2/F | P |
|---|---|---|---|---|---|---|
| Gender |
Male(110) Female(123) |
53 (0.48) 64 (0.52) |
9 (0.08) 11 (0.09) |
48 (0.44) 48 (0.39) |
0.510 | 0.775 |
|
Age of onset (years, Χ ± S) |
24.06 ± 7.77 | 26.70 ± 7.14 | 23.99 ± 6.90 | 1.205 | 0.302 | |
| Onset form |
Acute(22) Subacute(28) Chronic(183) |
10 (0.46) 14 (0.50) 93 (0.51) |
4 (0.18) 0 (0) 16 (0.09) |
8 (0.36) 14 (0.50) 74 (0.40) |
5.560 | 0.235 |
|
Duration (months, Χ ± S) |
97.94 ± 96.04 | 109.00 ± 105.4 | 99.56 ± 96.45 | 0.111 | 0.895 | |
| Family history |
Positive(162) Negative(71) |
73 (0.45) 44 (0.62) |
14 (0.09) 6 (0.08) |
75 (0.46) 21 (0.30) |
6.162 | 0.046 |
| Interpersonal relationship |
Good(15) General(123) Poor(95) |
8 (0.53) 67 (0.54) 42 (0.44) |
2 (0.13) 11 (0.09) 7 (0.08) |
5 (0.34) 45 (0.37) 46 (0.48) |
3.794 | 0.435 |
| Premorbid character |
Extro(37) Neutral(14) Intro(182) |
20 (0.54) 7 (0.50) 90 (0.49) |
2 (0.05) 1 (0.07) 17 (0.09) |
15 (0.41) 6 (0.43) 75 (0.41) |
0.734 | 0.947 |
| Marital status |
Unmarried(116) Married(75) Living apart(10)Divorced(28) Loss of spouse(4) |
59 (0.51) 39 (0.52) 5 (0.50) 14 (0.50) 0 (0) |
8 (0.07) 6 (0.08) 3 (0.30) 2 (0.07) 1 (0.25) |
49 (0.42) 30 (0.40) 2 (0.20) 12 (0.43) 3 (0.75) |
11.423 | 0.179 |
| State of occupation |
Full-time(64) Part-time(38) Jobless*(93) Unemployment*(9) Retired(28) Other works(1) |
32 (0.50) 19 (0.50) 43 (0.46) 7 (0.78) 15 (0.54) 1 (1) |
5 (0.08) 3 (0.08) 9 (0.10) 0 (0) 3 (0.10) 0 (0) |
27 (0.42) 16 (0.42) 41 (0.44) 2 (0.22) 10 (0.36) 0 (0) |
5.027 | 0.889 |
| PANSS(Χ ± S) | Positive score | 27.74 ± 4.17 | 28.05 ± 4.05 | 28.52 ± 5.40 | 1.299 | 0.541 |
| PANSS(Χ ± S) | Negative score | 23.72 ± 5.45 | 24.10 ± 4.52 | 23.80 ± 5.11 | 0.046 | 0.955 |
| PANSS(Χ ± S) | psychopathology | 47.74 ± 7.02 | 49.80 ± 7.75 | 48.44 ± 7.12 | 0.798 | 0.452 |
| PANSS(Χ ± S) | Total score | 99.20 ± 11.46 | 101.95 ± 10.43 | 100.76 ± 11.35 | 0.801 | 0.450 |
Notes: Bolded indicates statistically significant (p < 0.05); Italics indicates Kruskal-Wallis test for non-parametric test, and the statistic is χ2. (Χ ± S) means (Mean ± Standard Deviation)
*“Jobless” represents patients whose job were lost because of disease. “Unemployment” represents patients who had never worked