Table 6.
Comparison of cognitive test scores in patients with different genotypes of rs12294045
| Subtests | rs12294045 | F | Ρ | Ρ 1 | Ρ 2 | Ρ 3 | ||
|---|---|---|---|---|---|---|---|---|
| CT(n = 96) | CC(n = 116) | TT(n = 20) | ||||||
| TMT-A | 45.23 ± 7.86 | 46.28 ± 11.97 | 47.95 ± 7.54 | 0.704 | 0.495 | 0.442 | 0.274 | 0.500 |
| Symbol Coding | 42.00 ± 10.56 | 40.98 ± 10.10 | 44.60 ± 11.07 | 1.113 | 0.330 | 0.473 | 0.308 | 0.149 |
| Category Fluency | 47.75 ± 11.32 | 47.35 ± 11.25 | 48.55 ± 10.88 | 0.105 | 0.901 | 0.805 | 0.772 | 0.664 |
| CPT-IP | 41.84 ± 11.11 | 42.05 ± 10.75 | 45.25 ± 13.08 | 0.823 | 0.441 | 0.914 | 0.213 | 0.228 |
| LNS | 43.76 ± 10.97 | 46.96 ± 11.32 | 50.75 ± 9.89 | 4.184 | 0.016 | 0.042 | 0.011 | 0.149 |
| WMS-III | 44.34 ± 12.03 | 44.68 ± 12.93 | 47.10 ± 12.63 | 0.413 | 0.662 | 0.914 | 0.373 | 0.399 |
| HVLT-R | 42.22 ± 12.18 | 44.94 ± 10.88 | 48.80 ± 11.08 | 3.222 | 0.042 | 0.098 | 0.020 | 0.154 |
| BVMT-R | 43.89 ± 11.79 | 43.16 ± 11.16 | 44.30 ± 13.07 | 0.192 | 0.826 | 0.598 | 0.884 | 0.655 |
| NAB-MAZES | 43.02 ± 8.99 | 42.94 ± 11.05 | 42.65 ± 10.70 | 0.013 | 0.987 | 0.914 | 0.883 | 0.930 |
| MSCEIT | 47.03 ± 12.30 | 48.09 ± 11.91 | 51.75 ± 14.55 | 1.222 | 0.297 | 0.568 | 0.120 | 0.209 |
Note: Bolded indicates statistically significant (p < 0.05)
Ρ 1 represents the comparison between CT genotype patients and CC genotype patients; Ρ 2 represents the comparison between CT genotype patients and TT genotype patients; Ρ 3 represents the comparison between CC genotype patients and TT genotype patients.(TMT-A Trail Making Test A, CPT-IP Continuous Performance Test-Identical Pairs, LNS Letter-Number Span Test, WMS-III Wechsler Memory Scale-Third Edition, HVLT-R Hopkins Verbal Learning Test-Revised, BVMT-R Brief Visuospatial Memory Test-Revised, NAB Neuropsychological Assessment Battery, MSCEIT Mayer-Salovey-Caruso Emotional Intelligence Test).