Table 3.

HADS¹ anxiety and depression score ≤ 7 in HUNT3 (n=18,380): Risk of elevated HADS¹ score in HUNT4 based on headache diagnoses in HUNT3 evaluated by poisson regression with 95% confidence interval

	Number	HADS anxiety score		HADS depression score		Total HADS score
		8-10 (n=1228)	≥ 11 (n=349)	8-10 (n=751)	≥ 11 (n=182)	15-21 (n=862)	≥ 22 (n=131)
		RR (95% CI)	RR (95% CI)	RR (95% CI)	RR (95% CI)	RR (95% CI)	RR (95% CI)
Model 1: Adjusted for age, gender and education level
Headache free	11,819	1.00	1.00	1.00	1.00	1.00	1.00
TTH2	3063	1.34 (1.10-1.55)	1.19 (0.90-1.57)	1.40 (1.16-1.69)	0.93 (0.60-1.43)	1.21 (1.01-1.44)	1.04 (0.64-1.68)
Definite migraine	1962	1.71 (1.46-2.00)	1.33 (0.97-1.81)	1.27 (1.00-1.63)	1.36 (0.87-2.12)	1.52 (1.24-1.85)	1.10 (0.63-1.91)
Without aura	1038	1.61 (1.31-1.96)	0.72 (0.42-1.21)	1.35 (0.98-1.85)	0.86 (0.42-1.77)	1.34 (1.02-1.76)	0.39 (0.12-1.29)
With aura	924	1.83 (1.50-2.29)	2.02 (1.42-2.88)	1.19 (0.84-1.70)	1.91 (1.13-3.22)	1.71 (1.31-2.21)	1.90 (1.04-3.35)
Probable migraine	1252	1.32 (1.07-1.62)	1.33 (0.91-1.94)	1.19 (0.90-1.59)	1.24 (0.72-2.18)	1.45 (1.14-1.85)	1.13 (0.59-2.21)
Model 2: Adjusted for age, gender, education level, smoking status and body mass index
Headache free	11,819	1.00	1.00	1.00	1.00	1.00	1.00
TTH2	3063	1.34 (1.16-1.57)	1.18 (0.89-1.56)	1.40 (1.16-1.68)	0.92 (0.59-1.42)	1.21 (1.01-1.44)	1.03 (0.64-1.67)
Definite migraine	1962	1.69 (1.45-1.98)	1.29 (0.94-1.77)	1.25 (0.98-1.61)	1.29 (0.82-2.02)	1.49 (1.22-1.82)	1.00 (0.57-1.74)
Without aura	1038	1.61 (1.31-1.96)	0.72 (0.42-1.21)	1.35 (0.98-1.85)	0.86 (0.42-1.77)	1.34 (1.02-1.76)	0.39 (0.12-1.29)
With aura	924	1.83 (1.50-2.29)	2.02 (1.42-2.88)	1.19 (0.84-1.70)	1.91 (1.13-3.22)	1.71 (1.31-2.21)	1.90 (1.04-3.35)
Probable migraine	1252	1.30 (1.06-1.60)	1.31 (0.89-1.92)	1.19 (0.89-1.58)	1.24 (0.71-2.17)	1.44 (1.13-1.82)	1.11 (0.57-2.16)

¹Hospital Anxiety and Depression Scale; ²Tension-type headache