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. 2022 Feb 19;27:16. doi: 10.1186/s11658-022-00316-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Validation of DEmNRAs and DElncRNAs by qPCR testing. A Five randomly picked upregulated DEmRNAs were examined via qPCR testing. B qPCR examination of the expression of three randomly picked downregulated DEmRNAs. C, D qPCR examination of the expression of certain representative DEmRNAs relevant with itch, pain, or inflammation process. E qPCR examination of the expression of four randomly selected upregulated DElncRNAs. F qPCR examination of the expression of two randomly selected upregulated DElncRNAs. *p < 0.05, **p < 0.01 versus control group. n = 6 mice per group