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. 2022 Mar 8;50:21. doi: 10.1186/s41182-022-00412-9

Table 2.

Clinical features and laboratory findings of the patients in acute stage (n = 143)

Clinical features n (%)
Fever 143 (100)
Symmetrical joint involvement 121 (84.6)
Joint involvement at onset
 Generalized 96 (67.1)
 Ankle 22 (15.4)
 Knee 15 (10.5)
 Others 10 (6.9)
Subsequent joint involvement
 Ankle 119 (83.2)
 Metacarpophalangeal joint 100 (69.9)
 Wrist 97 (67.8)
 Proximal interphalangeal joints 84 (58.7)
 Knee 76 (53.1)
 Shoulder 64 (44.8)
 Elbow 51 (35.7)
 Metatarsophalangeal joint 46 (32.2)
 Distal interphalangeal joints 43 (30.1)
 Others (hip, temporomandibular joint, axial plane) 30 (20.9)
Joint swelling 68 (47.6)
Morning stiffness 117 (81.8)
Myalgia 47 (32.9)
Skin involvement 91 (63.6)
Pattern of skin involvement
 Pruritic erythematous rash 67 (46.9)
 Erythematous rash 24 (16.8)
Functional disability
 Mild 79 (55.2)
 Moderate 49 (34.3)
 Severe 15 (10.5)
Laboratory findings
Positive Immunoglobulin M (IgM) 135 (94.4)
Positive Immunoglobulin G (IgG) 29 (20.3)
C-reactive protein (CRP) positive (n = 48) 39 (81.2)
Erythrocyte sedimentation rate (mm in 1st hour), median [IQR] 31.0 [15.0–45.0]
White blood cells count (103/µL), mean ± SD 8.4 ± 2.4
Platelet count (103/µL) mean ± SD 297.1 ± 91.7
Serum creatinine (mg/dl) 0.8 ± 0.2

*IQR Inter-quartile range