Table 1.
Demographical profiles and clinical variables at evaluation times in HFEM and CM patients
HFEM (n = 47) | CM (n = 107) | |
---|---|---|
Age years, mean (SD) | 48.9 (11.2) | 49.4 (11.2) |
Sex % (n females) | 78.7 (37) | 69.2 (74) |
BMI kg/m2, median (25th,75th) | 22.00 (20.43,23.63) | 23.20 (22.00,25.70) |
Baseline MOH % (n) | 9.7 (10) | 90.3 (93) |
Treatment % (n Erenumab) | 51.1 (24) | 62.6 (67) |
MMDs median (25th,75th) | ||
Baseline | 11.0 (10.0,13.75) | 20.0 (16.0,30.0) |
last month | 6.0 (4.0,9.0) | 9.0 (5.7,14.3) |
follow-up 1 month | 9.0 (8.0,11.0) | 14.5 (10.0,18.0) |
follow-up 2 month | 10.5 (9.2,11.7) | 16.0 (10.7,20.0) |
follow-up 3 month | 10.5 (9.0,13.5) | 15.0 (10.7,22.0) |
RR median (25th,75th) | ||
last month | −63.6 (−84.7,-60.0) | −61.1 (-77.3, -40.0) |
follow-up 1 month | −42.9 (−87.9,-42.5) | −46.6 (-69.6, -15.4) |
follow-up 2 month | −28.6 (−71.5,–20.5) | −40.0 (-55.6, -10.0) |
follow-up 3 month | −14.3 (−65.9,-10.3) | −30.0 (-55.0, -6.7) |
last month - follow-up 3 difference | −47.7 (−79.5,-17.0) | −25.5 (−47.1,-3.3) |
MPI median (25th,75th) | ||
Baseline | 12.0 (10.5,14.5) | 21.0 (15.0,32.0) |
last month | 4.0 (2.0,7.0) | 7.0 (4.0,13.0) |
follow-up 1 month | 6.0 (2.5,11.0) | 8.0 (5.0,15.0) |
follow-up 2 month | 9.0 (5.5,12.5) | 12.0 (8.0,18.0) |
follow-up 3 month | 10.0 (6.0,13.5) | 15.0 (9.0,22.0) |
NRS median (25th,75th) | ||
Baseline | 7.5 (7.0,8.0) | 7.0 (7.0,8.0) |
last month | 6.0 (4.0,6.2) | 5.0 (4.0,7.0) |
follow-up 1 month | 6.0 (4.7,7.0) | 6.0 (4.0,7.0) |
follow-up 2 month | 6.0 (4.7,7.0) | 6.0 (5.0,7.0) |
follow-up 3 month | 7.0 (5.0,7.0) | 7.0 (5.0,8.0) |
Hit-6 median (25th,75th)[n] | ||
Baseline | 66.5 (64.7,70.0) [33] | 67.0 (64.0,72.0) [83] |
last month | 51.0 (41.5,60.0) [24] | 55.0 (50.0,62.0) [57] |
follow-up 1 month | 56.0 (31.5,62.3) [20] | 60.0 (53.0,66.0) [51] |
follow-up 2 month | 61.5 (51.5,65.0) [22] | 62.0 (53.5,66.5) [51] |
follow-up 3 month | 60.5 (48.3,65.3) [37] | 63.0 (51.0,68.0) [75] |