. 2022 Mar 8;18:91. doi: 10.1186/s12917-022-03185-9

Table 6.

Comparison of the results of mecA PCR and cefoxitin/oxacillin resistance among Staphylococcus spp. isolated from canine specimens submitted to a veterinary diagnostic laboratory in Tennessee, USA (2006–2017)

Organism	Drug	Interpretation	*mecA* positive		*mecA* negative		Percent	κ^a	95% CI^b		p-value
Organism	Drug	Interpretation	Percent	Number	Percent	Number	agreement	κ^a	95% CI^b		p-value
S. pseudintermedius	Cefoxitin	Resistant	97.4	1160/1191	2.6	31/1191	74.9%	0.522	0.497	0.548	< 0.0001
		Susceptible	37.9	797/2104	62.1	1307/2104
	Oxacillin	Resistant	95.4	1908/2001	4.7	93/2001	95.4%	0.904	0.889	0.919	< 0.0001
		Susceptible	4.6	60/1311	95.4	1251/1311
S. aureus	Cefoxitin	Resistant	96.7	117/121	3.3	4/121	95.3%	0.834	0.714	0.953	< 0.0001
		Susceptible	12.0	3/25	88.0	22/25
	Oxacillin	Resistant	95.9	117/122	4.1	5/122	94.0%	0.787	0.653	0.920	< 0.0001
		Susceptible	16.0	4/25	84.0	21/25
S. coagulans	Cefoxitin	Resistant	94.4	151/160	5.6	9/160	76.3%	0.525	0.460	0.590	< 0.0001
		Susceptible	31.1	121/389	68.9	268/389
	Oxacillin	Resistant	95.3	261/274	4.7	13/274	95.6%	0.913	0.878	0.947	< 0.0001
		Susceptible	4.0	11/275	96.0	264/275
S. schleiferi	Cefoxitin	Resistant	97.4	37/38	2.6	1/38	59.1%	0.291	0.182	0.400	< 0.0001
		Susceptible	57.3	51/89	42.7	38/89
	Oxacillin	Resistant	98.9	87/88	1.1	1/88	97.7%	0.945	0.884	1.000	< 0.0001
		Susceptible	5.0	2/40	95.0	38/40

^aKappa statistic for test of agreement

^bConfidence interval