Figure 1.

Neutralizing activities against WT SARS-CoV-2 and variants in convalescent individuals received the inactivated vaccine. (a) Plasma neutralizing activities against each SARS-CoV-2 strain in three follow-up time points were measured and shown in the values of 50% inhibition dilution (ID₅₀). (b) The broad spectrum of plasma nAbs in three follow-up time points. The GMT of nAbs against each variant was compared to that against WT, respectively. The positive rates of nAbs were marked at the bottom of each column. (c) The durability of broadly nAbs post the boosted vaccination. Paired plasma samples were collected from five individuals at Week 2 (n = 4) or Week 4 (n = 1) and Month 3 post vaccination and then tested the neutralizing activities against WT SARS-CoV-2 and variants. “-” represents decreased neutralization activity, “+” represents increased neutralization activity. The paired t test is performed here. “****” means P < .0001, “***” means P < .001, “**” means P < .01, “*” means P < .05, “ns” means not significant. The GMT, fold-change, and significance of difference were labeled on the top. The limit of detection was 1:20 dilution. The data below the limit was set to 20 for visualization.