Table 3.
In vitro release kinetics for the prepared PIP loaded BLs.
| Release model | Formulation code |
|||||||
|---|---|---|---|---|---|---|---|---|
| CU Susp. | PIP Susp. | F1 | F2 | F3 | F4 | F5 | F6 | |
| Higuchi | R2 = 0.935 | R2 = 0.952 | R2 = 0.964 | R2 = 0.567 | R2 = 0.663 | R2 = 0.963 | R2 = 0.663 | R2 = 0.583 |
| First order | R2 = 0.760 | R2 = 0.840 | R2 = 0.868 | R2 = 0.945 | R2 = 0.99 | R2 = 0.90 | R2 = 0.977 | R2 = 0.975 |
| Zero order | R2 = 0.447 | R2 = 0.690 | R2 = 0.283 | R2 = 0.548 | R2 = 0.689 | R2 = 0.38 | R2 = 0.687 | R2 = 0.671 |
The bolded and underlined values are the highest values of correlation coefficient (R2) representing the kinetic model that best fit the drug release mode of each formula.