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Serum exposures and pharmacokinetics for the 3- and 5-day regimens
| Parameter (units) | Mean ± SD for regimen
|
P value | |
|---|---|---|---|
| 3 Day | 5 Day | ||
| AUC0–∞ (mg · h/liter) | 19.4 ± 7.9 | 15.9 ± 4.8 | 0.06 |
| t1/2 (h) | 65.9 ± 14.7 | 66.1 ± 10.5 | 0.75 |
| CLt/F (liters/h) | 90.6 ± 38.7 | 102.5 ± 29.8 | 0.18 |
| Vss/F (liters/kg) | 121.2 ± 32.8 | 143.9 ± 33.1 | 0.03 |
