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. 2021 Oct 29;17(12):5475–5486. doi: 10.1080/21645515.2021.1983387

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© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 2. — Immunogenicity primary objective: Superiority of IIV4-HD compared with IIV4-SD using GMTs at D 28 after vaccination – Full Analysis Set. (a) Geometric mean titer ratios for each strain in each analysis group. GMTRs calculated as geometric mean of individual ratios at D 28 and 0. Labels GMTR (95% CI). (b) GMTRs for each strain in each analysis group. GMT, geometric mean titer; GMTR, geometric mean titer ratio; IIV4-HD, quadrivalent high-dose inactivated influenza vaccine; IIV4-SD, standard-dose quadrivalent influenza vaccine.