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. 2022 Feb 25;49(4):54. doi: 10.3892/ijmm.2022.5110

Figure 2.

Figure 2

Myricetin induces apoptotic cell death in SK-BR-3 cells. (A) Fluorescence microscopic images of SK-BR-3 cells treated with myricetin (10 and 20 µM for 24 h) and stained with DAPI. The arrows indicate chromatin condensation in SK-BR-3 cells. Scale bar, 10 µm. (B) Flow cytometry results of SK-BR-3 cells treated with myricetin (10 and 20 µM for 24 h) and were stained with Annexin V/PI. (C) The bar graph represents the apoptotic bodies (% of total cells). (D) Total cell population (%) in groups treated with 0, 10, and 20 µM of myricetin. The control group (0 µM) was treated with the same amount of DMSO. Data are displayed as the mean ± SD (n=3). *P<0.05 vs. control group. DAPI, 4′, 6-diamidino-2-phenylindole; PI, propidium iodide; DMSO, dimethyl sulfoxide.