Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Feb 18;49(4):53. doi: 10.3892/ijmm.2022.5109

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Feng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Wogonin reduces oxidative damage and cell apoptosis by regulating the PI3K/Nrf2/HO-1 pathway. (A) Western blotting analysis showed NOX², caspase-3, Bax and Bcl-2 protein levels in the rat hippocampus at 24 h from the sham group, TBI group, TBI + Wog group, TBI + Wog + LY group and TBI + DMSO group. (B-E) The optical density of NOX², caspase-3, Bax and Bcl-2 bands relative to β-actin was analyzed. ^*P<0.05 vs. sham group; ^#P<0.05 vs. TBI group; ^$P<0.05 vs. TBI + Wog group; ^&P< vs. TBI + Wog + LY group. Nrf2, nuclear factor-erythroid factor 2-related factor 2; HO-1, heme oxygenase-1; TBI, traumatic brain injury.