Table 4.
Diagnostic value of the combinations of autoantibodies.
| Panel of TAAbs | Positive, No. (%) | Se, (%) | Sp (%) | YI | LR+ | LR- | PPV (%) | NPV, (%) | Accuracy (%) | |
|---|---|---|---|---|---|---|---|---|---|---|
| OC (n = 136) | NHC (n = 136) | |||||||||
| LRDD | 67 (49.26) | 13 (9.56) | 49.26 | 90.44 | 0.40 | 5.15 | 0.56 | 83.75 | 64.06 | 69.85 |
| LRDD, FOXA1 | 79 (58.09) | 17(12.50) | 58.09 | 87.50 | 0.46 | 4.65 | 0.48 | 82.30 | 67.61 | 72.79 |
| LRDD, FOXA1, STC1 | 81 (59.56) | 20 (14.71) | 59.56 | 85.29 | 0.45 | 4.05 | 0.47 | 80.20 | 67.84 | 72.43 |
Abbreviations: OC: ovarian cancer; NHC: normal healthy controls; Se: sensitivity; Sp: specificity; YI: Youden index; LR+: positive likelihood ratio; LR−: negative likelihood ratio; PPV: positive predictive value; NPV: negative predictive value.