Fig. 1.

Overview of study design and antibody measurements for Thai symptomatic and asymptomatic longitudinal cohorts. The length of the bars represents the duration of the study. The Thai symptomatic patients were all recruited at the time of clinical P. vivax infection then followed for 9 months. The Thai asymptomatic individuals were selected from an existing yearlong observational cohort [32]. Individuals were selected who had an asymptomatic P. vivax infection within the first 6 months of the study as determined by PCR during surveillance. Total IgG antibody measurements were made at the time of P. vivax infection and then at all available following time points