Table 1.

National uptake of HPV vaccination programme pre- and post-intervention period, by local authorities

	Pre-intervention			Post-intervention
	Eligible	HPV vaccine dose one uptake		Eligible	HPV vaccine dose one uptake		Risk difference
	N	% (SE)	P-value	N	% (SE)	P-value	% (SE)	P-value
England overall	587,610	87.5 (0.3)		620,878	87.1 (0.3)		−0.4 (0.4)	0.36
Intervention site: Local Authority One	2022	Mean (0.1)		2362	Mean (1.7)		+6.2 (1.7)	0.17
Comparator local authorities	1367	85.2 (1.6)		1504	79.9 (1.6)		−5.3 (2.3)	0.04
Difference: Local Authority One-comparator		−8.8 (3.4)	0.02		2.6 (3.4)	0.45	+11.5 (4.8)*	0.03
Intervention site: Local Authority Two	1221	84.8 (2.4)		1381	87.3 (0.1)		+2.4 (2.4)	0.49
Comparator local authorities	2733	87.1 (0.6)		2809	88.2 (1.2)		+1.0 (1.3)	0.43
Difference: Local Authority Two-Comparator		−2.3 (2.9)	0.42		−0.9 (2.9)	0.76	+1.5 (3.6)*	0.72

Pre-intervention period, 2015–2016 to 2016–2017; post-intervention period, 2017–2018 to 2018–2019; HPV, human papillomavirus; SE, standard error.

^*Difference-in-differences.