Table 2.
Gene set enrichment analysis of fetal rabbit to vs. Control.
| GO molecular function | GO biological function | Topp cell atlas | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Term | No. genes | % Genes | q-value | Term | No. Genes | % Genes | q-value | Term | No. Genes | % Genes | q-value |
| DNA replication origin binding | 5 | 5% | 3.65E-05 | pre-replicative complex assembly | 5 | 5% | 1.34E-10 | Cycling Basal Cell (Mouse Trachea) | 20 | 20% | 6.43E-24 |
| Calcium ion binding | 15 | 15% | 2.68E-03 | pre-replicative complex assembly involved in cell cycle DNA replication | 5 | 5% | 1.34E-10 | Basal Cell (Mouse Trachea) | 17 | 17% | 2.83E-19 |
| Glycosaminoglycan binding | 8 | 8% | 1.60E-02 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication | 5 | 5% | 1.34E-10 | Dividing T-cell | 17 | 17% | 2.09E-18 |
| Extracellular matrix structural constituent | 7 | 7% | 1.65E-02 | regulation of cell population proliferation | 32 | 33% | 3.83E-10 | Activated T cell | 17 | 17% | 3.55E-18 |
| DNA helicase activity | 5 | 5% | 1.73E-02 | tube development | 26 | 27% | 4.08E-10 | Dividing Alveolar Macrophage | 16 | 16% | 1.17E-16 |
| Single-stranded DNA binding | 6 | 6% | 1.92E-02 | circulatory system development | 26 | 27% | 6.62E-10 | Neuroepithelial cell | 16 | 16% | 1.77E-16 |
| 3'-5' DNA helicase activity | 3 | 3% | 3.88E-02 | vasculature development | 21 | 21% | 1.73E-09 | Developing Plasmablast | 16 | 16% | 1.77E-16 |
| Single-stranded DNA helicase activity | 3 | 3% | 4.59E-02 | double-strand break repair via break-induced replication | 5 | 5% | 1.86E-09 | Early Lung Fibroblast Progenitor | 14 | 14% | 5.64E-14 |
| Cell adhesion molecule binding | 11 | 11% | 5.59E-02 | cell adhesion | 27 | 28% | 4.03E-09 | AT1-AT2 progenitors | 14 | 14% | 2.24E-13 |
| Catalytic activity, acting on DNA | 7 | 7% | 5.79E-02 | biological adhesion | 27 | 28% | 4.44E-09 | B-cell | 14 | 14% | 2.41E-13 |