TABLE 2.
Predictors of the most advanced findingsa on colonoscopy (N = 29,105) based on random effects model for ordinal data, accounting for clustering of data by endoscopist (N = 169)
| Variable | Odds ratiob | p |
|---|---|---|
| Age (5-year increments; ref = age 65–69) | 1.09 [1.07–1.12] | <0.0001 |
| Male (ref = female) | 1.62 [1.54–1.70] | <0.0001 |
| BMI (ref normal) | ||
| Underweight | 0.96 [0.80–1.15] | 0.65 |
| Overweight | 1.12 [1.05–1.19] | <0.0001 |
| Obese | 1.37 [1.28–1.46] | <0.0001 |
| Former or current smoker (ref = never smoker) | 1.16 [1.10–1.21] | <0.0001 |
| Alcohol intake (≥5 vs. <4 drinks/week) | 1.10 [1.04–1.16] | <0.0001 |
| Exercise (≥1 vs. <1 times/week) | 0.84 [0.80–0.88] | <0.0001 |
| History of colorectal cancer | 0.93 [0.84–1.03] | 0.18 |
| Family history of colorectal cancer in first-degree relative | 1.07 [1.01–1.13] | 0.022 |
| Indication (ref = screening) | ||
| Surveillance | 1.38 [1.31–1.45] | <0.0001 |
| Diagnostic | 0.95 [0.87–1.02] | 0.18 |
a
Most advanced findings ordered as no significant findings, non-advanced polyps, and advanced neoplasia.
b
Interpretation of odds ratio: For age, the odds ratio is 1.09, meaning that for every 5-year increase in age, there is a 9% higher odds of having an advanced finding on colonoscopy.