Table 1.
Patient ID | Age at B0 [years] | Gender | Asthma severity (GINA 2005) | Asthma control (GINA 2009) | Treatment | PBMC SN PHA IL3 [pg/ml] |
---|---|---|---|---|---|---|
A1 | 6 | Male | I | Controlled | Steroid | 152,182 |
A2 | 6 | Male | II | Partially controlled | Steroid | 75,870 |
A3 | 5 | Female | II | Partially controlled | Steroid | 22,678 |
A4 | 6 | Male | II | Controlled | Steroid | 48,344 |
A5 | 5 | Male | I | Partially controlled | Steroid | 25,122 |
A6 | 5 | Female | I | Controlled | Steroid | 51,480 |
A7 | 5 | Male | I | Partially controlled | Steroid | 58,026 |
A9 | 4 | Female | n.a. | Partially controlled | Steroid | n.m. |
A10 | 6 | Female | I | Partially controlled | Non-steroid | n.m. |
A12 | 5 | Male | II | Controlled | Steroid | n.m. |
A13 | 4 | Male | III | Partially controlled | Steroid | 38,544 |
A16 | 5 | Female | III | Uncontrolled | Steroid | 6,436 |
A17 | 6 | Female | I | Uncontrolled | Steroid | 0,000 |
A23 | 5 | Male | I | Controlled | Steroid | 14,320 |
A24 | 4 | Female | I | Controlled | Steroid | 64,980 |
A25 | 4 | Male | I | Controlled | Steroid | 0,000 |
A28 | 5 | Male | I | Controlled | Non-steroid | 0,000 |
A29 | 4 | Male | I | Controlled | Non-steroid | 5,082 |
A30 | 5 | Male | I | Controlled | Non-steroid | 0,000 |
A31 | 4 | Male | I | Partially controlled | Steroid | 0,000 |
A38 | 4 | Male | I | Controlled | Steroid | 50,610 |
A39 | 5 | Female | I | Controlled | Non-steroid | 0,000 |
A42 | 5 | Male | II | Controlled | Steroid | 0,000 |
A43 | 5 | Female | II | Uncontrolled | Steroid | 0,000 |
Asthma severity: I = intermittent: FEV1 > 80%; MEF > 65%; symptom-free interval > 2 months. II = mild persistent: FEV1 > 80%; MEF > 65%; symptom-free Interval < 2 months. III = moderate persistent: FEV1 < 80%; MEF < 65%; symptoms several days a week. IV = severe persistent: FEV1 < 60%; symptoms during the day and night.
FEV1, forced expiratory volume in 1 s; MEF, maximal expiratory flow; PBMC, peripheral blood mononuclear cell; PHA, phytohemagglutinin.