Table 10.
Hallmark term-related target enrichment in cancer driver genes.
Hallmark | miRNAsa | Targetsb | Overlapc | p-valued |
---|---|---|---|---|
Complement | 5 | 42 | 3 | 0.018 |
E2F Targets | 2 | 85 | 4 | 0.026 |
MTORC1 Signaling | 1 | 12 | 2 | 0.011 |
Myogenesis | 12 | 44 | 3 | 0.020 |
P53 Pathway | 1 | 12 | 2 | 0.011 |
TNFA Signaling via NFKB | 2 | 17 | 2 | 0.021 |
Pancreas Beta Cells | 2 | 48 | 3 | 0.026 |
aNo. of miRNAs in cancer hallmark term; bNo. of targets in the term; cNo. of overlapping targets in the cancer driver genes; dHypergeometric p-value of the overlap.