Table 4.
Comparison results of miRDriver with five other methods in ovarian cancer.
Method | Input miRNAs | Input genes | Computed miRNAs | Selected genes | Eligible miRNAsa | Overlapping eligible miRNAsb | Method's computed miRNAs in overlap | miRDriver's computed miRNAs in the overlap |
---|---|---|---|---|---|---|---|---|
miRDriver | 198 | 2114 | 147 | 354 | 27 | NA | NA | NA |
ARACNe | 198 | 2114 | 196 | 791 | 59 | 27 | 1 | 24 |
ProMise | 198 | 2114 | 57 | 1938 | 34 | 22 | 0 | 17 |
hiddenICP | 198 | 2114 | 198 | 2100 | 47 | 21 | 0 | 16 |
idaFast | 50 | 1500 | 50 | 1194 | 32 | 22 | 0 | 17 |
jointIDA | 50 | 1500 | 50 | 1294 | 32 | 22 | 0 | 17 |
aEligible miRNAs had at least one known target in the ground truth data; bOverlapping eligible miRNAs were with respect to miRDriver. For miRDriver, the number of significant miRNAs in every overlap with other methods was much higher. NA means not applicable.