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. 2022 Jan 14;30(3):349–362. doi: 10.1038/s41431-021-00987-7

Table 4.

External validation of PRS models in East Asian and African Populations.

Model East Asian ancestries African ancestries
AUC OR 95% CI AUC OR 95% CI
Lasso 0.541 1.16 (1.11–1.22) 0.576 1.28 (1.13–1.45)
Elastic net 0.543 1.17 (1.12–1.23) 0.574 1.29 (1.14–1.47)
Stepwise (OCAC) 0.528 1.11 (1.06–1.16) 0.581 1.34 (1.18–1.52)
Select and shrink (OCAC) 0.538 1.14 (1.08–1.19) 0.593 1.38 (1.21–1.58)
Stepwise (OCAC-CIMBA) 0.542 1.17 (1.11–1.23) 0.594 1.37 (1.20–1.56)
Select and shrink (OCAC-CIMBA) 0.537 1.14 (1.08–1.19) 0.596 1.41 (1.23–1.61)