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Adverse events in the 47 patients undergoing apatinib for radioiodine-refractory thyroid cancer.
| Adverse events | Number | |
|---|---|---|
| All grades | Grades 3/4 | |
| Hematologic toxicity | ||
| Leucopenia | 5 | 1 |
| Granulocytopenia | 3 | 1 |
| Thrombocytopenia | 2 | 1 |
| Non-hematologic toxicity | ||
| Hypertension | 20 | 5 |
| Proteinuria | 19 | 5 |
| Hand–foot skin reaction | 16 | 4 |
| Diarrhea | 6 | 2 |
| Liver dysfunction | 5 | 2 |
| Fatigue | 5 | 0 |
| Emesia | 4 | 0 |
| Nausea | 3 | 0 |
| Bleeding | 2 | 0 |
| Bellyache | 1 | 0 |
