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. 2022 Mar 8;12:3764. doi: 10.1038/s41598-022-07829-6

Table 4.

Sensitivity and specificity as determined by ROC analysis.

Biomarker Cutoff Sensitivity (%) Specificity (%)
K+ 29.799043 80.0 62.5
Na+ 148.350000 80.0 40.0
LDH 207.648000 80.0 55.0
GST 8.281250 80.0 77.5
MRC1 3.972000 80.0 40.0
PC1 1.217333 80.0 77.5
Disc1 −0.227751 80.0 87.5
PProb 0.436506 80.0 85.0
Caspase 7 30 27 57
Coenzyme Q10 30 27 57
Melatonin 32 29 61

PC1 first principal component scores computed in principal component analysis, Disc1 first discriminant scores computed in discriminant analysis, PProb predicted probability computed by binary logistic regression, K+ plasma potassium, Na+ plasma sodium, LDH plasma lactate dehydrogenase, GST plasma glutamate S-transferase, MRC1 mitochondrial respiratory chain complex I activity.