Table 4.

Association between Frailty Status and Use of DOAC vs. Warfarin, among Those Receiving OAC (N=121839)

Frail status	Number of patients	Percent on DOAC	Odds ratio (95% confidence interval) for DOAC
			Crude	Adjusted*
Non-frail	40,037	26	Reference	Reference
Pre-frail	42,756	28	1.12 (1.08,1.15)	1.27 (1.22, 1.31)
Frail	39,046	29	1.25 (1.21, 1.29)	1.75 (1.67, 1.83)

*Model adjusted for gender, race, marital status, depression, current smoker, heart failure, vascular disease, hypertension, diabetes, intracranial bleeding, GI bleeding, anemia, stroke, alcohol abuse, VA entitlement, CKD stage, medication count, BMI, admission 4 weeks prior, clopidogrel, prasugrel, ticagrelor, statin, beta blocker, and ACEI/ARB. Values in Bold indicate p<0.05