Table 2.

Univariate and multivariate cox regression analysis of disease-free survival.

Characteristics	Univariate cox analysis		Multivariate cox analysis
	Hazard ratio (95%CI)	p value	Hazard ratio (95%CI)	p value
Age (year)
≤50	Reference		Reference
>50	1.723 (1.056–2.810)	0.029*	1.370 (0.810–2.310)	0.243
BMI
≤23	Reference
>23	0.946 (0.581-1.540)	0.823
Menstrual status
Premenopausal	Reference
Postmenopausal	1.601 (0.974–2.632)	0.064
Histological grade a
1/2	Reference
3	0.988 (0.605–1.613)	0.961
Lymphovascular invasion
No	Reference		Reference
Yes	2.324 (1.358–3.979)	0.002*	1.560 (0.840–2.880)	0.157
Ki-67 index at diagnosis < 30% b
No	Reference
Yes	1.135 (0.655–1.964)	0.652
T stage c
1	Reference		Reference
2	0.863 (0.506–1.474)	0.590	0.840 (0.490–1.460)	0.543
3	1.021 (0.415–2.508)	0.964	0.890 (0.350–2.250)	0.802
4	3.886 (1.165–12.970)	0.027*	2.660 (0.770–9.270)	0.123
N stage c
0	Reference		Reference
1	2.452 (1.325–4.538)	0.004*	2.360 (1.250–4.430)	0.008*
2	2.898 (1.381–6.083)	0.005*	2.560 (1.190–5.500)	0.016*
3	5.788 (2.925–11.453)	<0.001*	4.130 (1.910–8.920)	<0.001*
IronMLR score
Low	Reference		Reference
High	2.157 (1.171–3.974)	0.014*	2.310 (1.200–4.430)	0.012*

*p＜0.05.

^aHistological grade at diagnosis was based on the degree of histological tumor differentiation.

^bThe Ki-67, index at diagnosis indicates DNA, synthetic activity as measured using immunocytochemistry.

^cDiagnosed based on the AJCC, 2010 criteria (seventh edition).