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. 2022 Mar 8;12:3773. doi: 10.1038/s41598-022-07518-4

Table 1.

Baseline characteristic by sampling phase.

1994–2005 2006–2008 2009–2011 2012–2014 2015–2017 2018–2020 Total P value
Sex
Men 169(70.71) 1162(86.07) 4162(95.68) 4714(96.5) 3651(95.48) 3293(92.5) 17,151(94.19)  < 0.05
Women 70(29.29) 188(13.93) 188(4.32) 171(3.5) 173(4.52) 267(7.5) 1057(5.81)
Age (years)a 32(26–38) 31(25–38) 31(26–39) 31(26–40) 31(26–44) 33(27–45) 32(26–42) NS
Ethnicity
Han 173(77.58) 756(76.06) 1790(91.42) 2505(93.54) 3648(95.57) 3442(96.69) 12,314(93.08)  < 0.05
Uyghur 40(17.94) 139(13.98) 54(2.76) 29(1.08) 27(0.71) 6(0.17) 295(2.23)
Yi 2(0.9) 35(3.52) 38(1.94) 34(1.27) 20(0.52) 12(0.34) 141(1.07)
Other 8(3.59) 64(6.44) 76(3.88) 110(4.11) 122(3.2) 100(2.81) 480(3.63)
CD4 count(cells per µl)b 299(181–402) 330(209–460) 345(202–455) 365(235–510) 326(204–462) 323(200–470) 338(208–475) NS
Transmission risk groups
Heterosexual 149(29.22) 616(31.4) 1045(19.27) 911(17.34) 837(21.96) 1227(34.51) 4785(23.32)  < 0.05
MSM 50(9.8) 742(37.82) 3581(66.03) 4120(78.42) 2867(75.23) 2295(64.54) 13,655(66.56)
Injecting drug user 111(21.76) 418(21.3) 712(13.13) 203(3.86) 107(2.81) 34(0.96) 1585(7.73)
Blood transfusion 190(37.25) 176(8.97) 79(1.46) 16(0.3) 0(0) 0(0) 461(2.25)
Mother to Child 10(1.96) 10(0.51) 6(0.11) 4(0.08) 0(0) 0(0) 30(0.15)
Region y199405 y200608 y200911 y201214 y201517 y201820  < 0.05
 North 104(19.85) 554(27.62) 1250(22.97) 1721(32.73) 1942(50.78) 1719(48.41) 7290(35.38)
 North-east 78(14.89) 104(5.18) 513(9.43) 393(7.47) 525(13.73) 561(15.8) 2174(10.55)
 East 79(15.08) 295(14.71) 1155(21.22) 1386(26.36) 461(12.06) 437(12.31) 3813(18.51)
 Central-south 148(28.24) 707(35.24) 1196(21.98) 1086(20.65) 464(12.13) 438(12.33) 4039(19.6)
 South-west 71(13.55) 162(8.08) 1180(21.68) 517(9.83) 234(6.12) 216(6.08) 2380(11.55)
 North-west 44(8.4) 184(9.17) 148(2.72) 155(2.95) 198(5.18) 180(5.07) 909(4.41)
Subtype
B 250(47.71) 602(29.86) 843(15.39) 570(10.84) 377(9.86) 235(6.6) 2877(13.92)  < 0.05
C 22(4.2) 31(1.54) 105(1.92) 55(1.05) 27(0.71) 19(0.53) 259(1.25)
01_AE 103(19.66) 679(33.68) 2423(44.23) 2586(49.16) 1797(46.98) 1568(44.04) 9156(44.31)
07_BC 89(16.98) 486(24.11) 1639(29.92) 1424(27.07) 1108(28.97) 1096(30.79) 5842(28.27)
08_BC 26(4.96) 103(5.11) 70(1.28) 93(1.77) 33(0.86) 32(0.9) 357(1.73)
55_01B 1(0.19) 28(1.39) 108(1.97) 149(2.83) 66(1.73) 99(2.78) 451(2.18)
Minor 14(2.67) 38(1.88) 115(2.1) 94(1.79) 101(2.64) 137(3.85) 499(2.41)
URF 19(3.63) 49(2.43) 175(3.19) 289(5.49) 316(8.26) 374(10.51) 1222(5.91)

Data are n (%), or median (IQR).

MSM, men who have sex with men; URF, unique recombinant form.

North, Beijing, Tianjin, Hebei, Shanxi, and Inner Mongolia. North-east, Liaoning, Jilin, and Heilongjiang. East, Shanghai, Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, and Shandong. Central- south, Henan, Hubei, Hunan, Guangdong, Guangxi, and Hainan. South-west, Chongqing, Sichuan, Guizhou, Yunnan, and Tibet. North-west, Shann'xi, Gansu, Qinghai, Ningxia, and Sinkiang.

Minor, A1, D, F1, G, H, CRF02_AG, CRF03_AB, CRF06_cpx, CRF15_01B, CRF18_cpx, CRF24_BG, CRF33_01B, CRF55_01B, CRF57_BC, CRF58_01B, CRF59_01B, CRF61_BC, CRF62_BC, CRF63_02A1, CRF64_BC, CRF65_cpx, CRF67_01B, CRF68_01B, CRF78_cpx, CRF79_0107, CRF82_cpx, CRF83_cpx, CRF85_BC, CRF86_BC, CRF87_cpx, CRF88_BC, and CRF96_cpx.

a13,216.

b10,439.