Table 2.
Comparison of the microbial relative abundances between pairwise groups according to renal stone status at the phylum, class, order, family, and genus levels.
| Taxonomic assignment | Wb (coefficientsc) | ||
|---|---|---|---|
| G0† vs. G1 | G0† vs. G2 | G1† vs. G2 | |
| p__Actinobacteriota | 14 (–0.30*) | 1 (–0.22) | 0 |
| p__Actinobacteriota; c__Actinobacteria | 15 (–0.22*) | 0 (–0.16) | 0 |
| p__Actinobacteriota; c__Coriobacteriia | 14 (–0.21*) | 0 (–0.15) | 0 |
| p__Fusobacteriota; c__Fusobacteria | 7 (0.15*) | 14 (0.22**) | 0 |
| p__Actinobacteriota; c__Actinobacteria; o__Bifidobacteriales | 32 (–0.23*) | 0 (–0.17) | 0 |
| p__Actinobacteriota; c__Actinobacteria; o__Bifidobacteriales; f__Bifidobacteriaceae | 54 (–0.23*) | 0 (–0.17) | 0 |
| p__Firmicutes; c__Clostridia; o__Lachnospirales; f__Lachnospiraceae; g__[Eubacterium]_eligens_group | 0 (–0.05) | 230 (–0.33**) | 0 |
| p__Firmicutes; c__Clostridia; o__Lachnospirales; f__Lachnospiraceae; g__Dorea | 210 (–0.25**) | 0 (–0.14) | 0 |
| p__Firmicutes; c__Clostridia; o__Oscillospirales; f__Ruminococcaceae; g__Incertae_Sedis | 206 (–0.25**) | 0 (0.03) | 0 |
| p__Firmicutes; c__Negativicutes; o__Veillonellales-Selenomonadales; f__Veillonellaceae; g__Dialister | 0 (0.05) | 201 (–0.28*) | 0 |
| p__Actinobacteriota; c__Actinobacteria; o__Bifidobacteriales; f__Bifidobacteriaceae; g__Bifidobacterium | 190 (–0.23*) | 0 (–0.17) | 0 |
| p__Firmicutes; c__Negativicutes; o__Acidaminococcales; f__Acidaminococcaceae; g__Phascolarctobacterium | 0 (0.13) | 176 (0.31*) | 0 |
| p__Firmicutes; c__Bacilli; o__Erysipelotrichales; f__Erysipelatoclostridiaceae; g__Erysipelatoclostridium | 0 (0.02) | 171 (0.20*) | 0 |
| p__Firmicutes; c__Clostridia; o__Lachnospirales; f__Lachnospiraceae; g__uncultured | 170 (–0.22**) | 0 (0.00) | 0 |
| p__Firmicutes; c__Clostridia; o__Oscillospirales; f__Ruminococcaceae; g__Faecalibacterium | 159 (–0.11*) | 0 (–0.07) | 0 |
p__: phylum, c__: class, o__: order, f__: family, g__: genus, s__: species, G0: no renal stone group, G1: incidental renal stone group, G2: prevalent renal stone group.
aNumber of phyla, 15; classes, 23; orders, 50; families, 89; genera, 260.
bW = X for taxon k, then H0k is rejected X times. The W statistics for the significantly different taxa relative to over 60% of the other taxa at each taxon level are represented in bold.
cCoefficients for the log-transformed relative abundance of each taxon in the linear model adjusted for age, sex, and BMI using MaAsLin2 on pairwise comparisons between groups. * p < 0.05, ** p < 0.01.
†Group used as the reference group in the regression model.