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. 2022 Mar 8;12:4043. doi: 10.1038/s41598-022-08049-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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T-ALL cell lines: Sensitivity to cytostatic drugs and glycolytic profile. Sensitivity of T-ALL cell lines to (A) ASNase, (B) VCR and (C) DNR based on MTS assays. (D) Glycolytic profile of T-ALL cell lines was determined using Seahorse XFp analyzer and Glycolysis Stress Test. (E) EC₅₀ values of ASNase, VCR and DNR in T-ALL cell lines. MTS assays were done at least in biological triplicates and six technical replicates. The Seahorse measurements were done at least in biological triplicates and six technical replicates. All the results are presented as a mean ± SD.