Table 3. The cox proportional hazard model of drug resistance-related genes and immune cells in LUAD (TIMER).
| Cells and genes | Coef. | HR | 95% CI_l | 95% CI_u | P value |
|---|---|---|---|---|---|
| B cell | −5.256 | 0.005 | 0.000 | 0.068 | 0.000*** |
| CD8+ T cell | 0.202 | 1.224 | 0.195 | 7.664 | 0.829 |
| CD4+ T cell | 2.827 | 16.901 | 1.133 | 252.102 | 0.040* |
| Macrophage | 0.014 | 1.014 | 0.077 | 13.307 | 0.991 |
| Neutrophil | −0.177 | 0.838 | 0.019 | 36.589 | 0.927 |
| Dendritic | −0.339 | 0.713 | 0.187 | 2.711 | 0.619 |
| CCDC73 | −0.194 | 0.823 | 0.404 | 1.677 | 0.592 |
| DLGAP1 | 0.150 | 1.161 | 0.956 | 1.411 | 0.132 |
| DSEL | 0.150 | 1.162 | 0.964 | 1.401 | 0.115 |
| ESR1 | 0.045 | 1.046 | 0.914 | 1.196 | 0.516 |
| SEC14L5 | 0.088 | 1.091 | 0.733 | 1.626 | 0.667 |
*, P<0.05; ***, P<0.001. LUAD, lung adenocarcinoma; coef., coefficient; HR, hazard ratio; 95% CI_I, lower bound of 95% confidence interval; 95% CI_u, upper bound of 95% confidence interval; CCDC73, coiled-coil domain-containing protein 73; DLGAP1, DLG associated protein 1; DSEL, dermatan sulfate epimerase like; ESR1, estrogen receptor 1; SEC14L5, SEC14-like 5.