Table 1. Correlation analysis of KIF2C gene expression level and patient clinical characteristics in The Cancer Genome Atlas database.
Variable | All cases (n=358) | KIF2C expression level | P value | |
---|---|---|---|---|
Low expression | High expression | |||
Age (years) | 0.026 | |||
≤60 | 172 | 75 | 97 | |
>60 | 186 | 103 | 83 | |
Sex | 0.132 | |||
Female | 242 | 127 | 115 | |
Male | 116 | 51 | 65 | |
Child-Pugh classa | 0.622 | |||
A | 209 | 112 | 97 | |
B | 22 | 13 | 9 | |
Alcohol historyb | 0.732 | |||
No | 223 | 110 | 113 | |
Yes | 117 | 60 | 57 | |
Hepatitis virusc | 0.303 | |||
No | 94 | 51 | 43 | |
Yes | 256 | 123 | 133 | |
Vascular invasiond | 0.235 | |||
No | 199 | 109 | 90 | |
Yes | 103 | 49 | 54 | |
Pathological stagee | 0.001 | |||
I | 165 | 96 | 69 | |
II | 81 | 36 | 45 | |
III + IV | 88 | 33 | 55 | |
Neoplasm histological gradef | <0.001 | |||
G1 | 53 | 38 | 15 | |
G2 | 169 | 91 | 78 | |
G3 + G4 | 131 | 47 | 84 | |
Cirrhosisg | 0.687 | |||
No | 72 | 29 | 43 | |
Yes | 139 | 60 | 79 | |
Radical resectionh | 0.154 | |||
R0 | 315 | 162 | 153 | |
R1/Rx | 36 | 14 | 22 |
a, Child-Pugh class was unavailable for 127 patients; b, alcohol history was unavailable for 18 patients; c, hepatitis virus was unavailable for 8 patients; d, vascular invasion was unavailable for 56 patients; e, pathological stage was unavailable for 24 patients; f, neoplasm histological grade was unavailable for 5 patients; g, cirrhosis was unavailable for 147 patients; h, radical resection was unavailable for 7 patients. KIF2C, kinesin family member 2C.