Table 2. Correlation between protein expression of AKT1 and clinicopathological features in 180 cases of NSCLC.
Factors | ATK1 protein expression (n=180) | P value | |
---|---|---|---|
Low expression (n=90) | High expression (n=90) | ||
Age | 0.1797 | ||
<60 years | 49 | 40 | |
≥60 years | 41 | 50 | |
Gender | >0.9999 | ||
Male | 46 | 46 | |
Female | 44 | 44 | |
TNM stage | 0.0006 | ||
I–II | 56 | 33 | |
III–IV | 34 | 57 | |
DDP | <0.0001 | ||
Sensitive | 64 | 26 | |
Resistant | 26 | 64 | |
Lymph node metastasis | <0.0001 | ||
Yes | 29 | 59 | |
No | 61 | 31 | |
Smoking status | 0.2967 | ||
Smoker | 49 | 42 | |
Non-smoker | 41 | 48 |
AKT1, AKT serine/threonine kinase 1; NSCLC, non-small cell lung cancer; DDP, cisplatin.