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. 2022 Feb;10(3):144. doi: 10.21037/atm-21-6915

Figure 3.

Figure 3

Screening the validated genes related to expression of PD-1 and PD-L1 in the GSE41613 cohort. (A) The genes positively correlated with PD-L1 expression. (B) The genes positively correlated with PD-1 expression. (C) Venn diagram showing the 3 genes (IL-12RB1, GPR25, and CTLA4) related to the expression of PD-1 and PD-L1. PD-1 (PDCD1), programmed cell death 1; PD-L1 (CD274), programmed death-ligand 1; IL-12RB1, interleukin 12 receptor subunit beta 1; GPR25, G protein-coupled receptor 25; CTLA4, cytotoxic T-lymphocyte associated protein 4; CCR5, C-C motif chemokine receptor 5; CD40LG, CD40 antigen ligand; CXCR3, C-X-C motif chemokine receptor 3; IDO1, indoleamine 2,3-dioxygenase 1; IGHV1-69, immunoglobulin heavy variable 1-69; IRF8, interferon regulatory factor 8; SH2D1A, SH2 domain containing 1A; TIGIT, T cell immunoreceptor with Ig and ITIM domains; TRAC, T cell receptor alpha constant; BTLA, B and T lymphocyte associated.